ENGINEERING AND SCIENCE RESEARCH LABS AND EQUIPMENT
Intensified TIRF Microscope
Assistant Professor, Department of Mechanical Engineering
This state-of-the-art imaging microscope system is the workhorse of experimental measurements in fluidic, colloidal, thermal, molecular and cellular research. The wide range of physical length scale (from mesoscale to molecular) and illumination means (Differential Interference Contrast, Total Internal Reflection, Multi-Color Fluorescence, Transillumination, Laser) provided by the microscope enables research in micro/nanofluidics, biofluidics, and biomolecule-fluidic interface interactions. In addition, the environment-controlled chamber enables prolonged measurements on temperature and humidity-sensitive specimen such as biological cells and molecules. A highly sensitive image intensifier is incorporated into the imaging arm of the microscope system to detect single photon events in the nanoscale. The whole imaging microscope is supported by a vibration-isolation optical table and housed in a dedicated dark room inside the Transport Science Core to ensure best imaging quality.