Wei Qiang's research interests focus on the biological application of the solid-state nuclear magnetic resonance (NMR) spectroscopy. His current projects include (1) understanding the structural basis and molecular mechanisms of the cellular membrane disruption induced by the early-stage aggregation of beta-amyloid peptides, (2) probing the mechanisms of the pH regulation of the pH-low insertion peptides and their applications in cancer diagnosis and treatment, and (3) designing the structure-specific bio bench markers and/or inhibitors to pathologically important beta amyloid fibrils. In addition to the solid-state NMR spectroscopy, he and his team utilize a combination of approaches including transmission electron microscopy, fluorescence spectroscopy, computational modeling as well as peptide and lipid chemistry.
- BS, Tsinghua University, China
- Solid-state nuclear magnetic resonance (NMR) spectroscopy.