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headshot of Yetrib Hathout

Yetrib Hathout

Professor

School of Pharmacy and Pharmaceutical Sciences

Background

Yetrib Hathout received his PhD in biochemistry/cellular and molecular biology from the University of Burgundy in Dijon, France. His PhD training was completed under the supervision of Bernard Maume in mass spectrometry studies of steroid synthesis pathways in cultured adrenocortical cells. Following his PhD, he took a postdoctoral position at the University of Maryland Baltimore County to work with Catherine Fenselau on characterization of proteins by mass spectrometry. Hathout then moved on to the University of Maryland in College Park where he served as staff scientist and continued working on developing mass spectrometry methods for rapid characterization of microorganisms and proteomics methods to study mechanisms of resistance of breast cancer cells to chemotherapy.

In 2004, Hathout joined the Research Center of Genetic Medicine, Children's Research Institute of the Children's National Health System in Washington, D.C., and was appointed as a tenure-track assistant professor of pediatrics at the George Washington University School of Medicine and Health Sciences. At Children's, Hathout worked at the interface between clinicians and basic scientists to develop proteomics and mass spectrometry methods to study pediatric diseases such as leukodystrophy, brain tumors and muscular dystrophies. He also served as a director of the proteomics facility at the center, working with investigators both within the institute and internationally to implement proteomics and advance the field of biomedical sciences.

In 2010, Hathout was promoted to associate professor with tenure and spearheaded a biomarker development program for Duchenne muscular dystrophy and other muscle diseases. His goal was to define non-invasive serum and urine biomarkers to monitor disease progression and response to therapies for muscle diseases.

In 2017, Hathout joined the School of Pharmacy and Pharmaceutical Sciences, Binghamton University as tenured professor. He received and continues to receive federal and foundation grants from the Department of Defense (DoD), the National Institutes of Health (NIH), the Muscular Dystrophy Association (MDA) and the French Muscular Dystrophy Association (AFM-Téléthon) to support his research projects on muscle diseases. Hathout is also overseeing and directing the proteomics facility at the Department of Pharmaceutical Sciences, fostering collaborations with investigators internally and externally.

An analytical chemist by training, Hathout has worked throughout his career to advance the fields of bio-analytical mass spectrometry. He has published more than 75 journal articles in the field of proteomics and mass spectrometry application to biomedical sciences. His complete list of publications can be found under the following URL.

Education

  • MS, University of Burgundy
  • PhD, University of Burgundy

Research Interests

  • Bio-analytical mass spectrometry and proteomics
  • Biomarker development
  • Neuromuscular diseases

Research Profile