Research

Biomedical engineering faculty play a leading role in a wide range of research activities at Binghamton University, both as individuals, as members of larger research groups or directing core research facilities.

Stem Cell and 3D Printing (Ye)

  • 3D Tissue and Organ Printing
  • Transitional Regenerative Medicine
  • Data-Driven Synthetic Biology
  • Single Molecule Imaging and Biosensing
  • Nanomedicine
  • Vaccine Development

Biological Soft Matter Mechanics Lab (German)

  • Multi-scale mechanics of heterogeneous tissues
  • Cell and tissue mechanobiology
  • Pathogenesis of skin infections and diseases
  • Cosmetic physics

Biomolecular and Tissue Engineering Lab (Jin) 

  • Human stem cell differentiation and interplay between cells and their microenvironments for tissue regeneration
  • Engineering tissue cues for in vitro maturation of stem cell-derived organoids
  • Engineering scaffold materials for organogenesis and organoid-on-a-chip platform
  • Development of nanosensors for real-time monitoring key parameters inside living systems
  • Vaccine development

In Vitro and In Silico Models of Organs and Tissues (Mahler) 

  • Biomechanical and biochemical cell signaling
  • Cell-cell and cell-extracellular matrix interactions
  • Cell behavior during disease and response to chemicals or drugs
  • Applications toward cardiovascular disease and cancer

Nanotechnology and Living Systems (Mahler)

  • Understanding how nanoparticles interact with biomolecules, cells, and tissues
  • Molecular changes in nanoparticle design affect the way that nanoparticles react to their environment
  • Nanotoxicity

Intimately Bio-integrated Biosensors (Koh)

  • Unconventional electrochemical biosensors
  • Flexible, stretchable, breathable sensors
  • Biocompatible sensors and materials
  • Wearable analytical devices for biomedical applications

Biophotonics and Computational Optical Bioimaging (Lu Group)

  • Stimualted Raman scattering (SRS) microscopy for label-free bioimaging applications
  • Live-cell imaging for lipid metabolism studies in cancer using SRS and multiphoton microscopy
  • SRS label-free AI-based digital pathology for image-guided brain tumor surgery  
  • Multiphoton ptychography for computational phase bioimaging
  • Imaging drug delivery using SRS microscopy and novel Raman tags

Pq Laboratory of Micro/Nano BiomeDx (Wan)

  • Developing micro/nano-devices and bioassays for disease early diagnosis
  • Translating the diagnostic and therapeutic techniques in clinical use
  • Investigating the biogenesis and biofunctions of extracellular vesicles in cancer

BioM2 Lab for Engineering Living Systems (Wang)

  • Multi-Organ Microphysiological Systems
  • Tissue Engineering
  • Microfluidic Tissue Culture Platforms
  • Integrated On-Chip Biosensing.

Facilities and Laboratories