C. Chen†, Y. Gu†, J. Rufo, J. Zhang, K. Yang, Y. Chen, L.P. Lee, and T.J. Huang, “Acoustofluidic
spin control for 3D particle manipulation in droplets”. Science Advances, Vol. 11, No.20, pp. eadx0269, 2025. († contributed equally to this work).
A. Tehrani, S. Schoen, I. Candel, Y. Gu, P. Guo, K. Thomenius, T.T. Pierce, M. Wang,
R. Tadross, M. Washburn, H. Rivaz, A. Samir, “Combining Deep Data-driven and Physics-inspired
Learning for Shear Wave Speed Estimation in Ultrasound Elastography”. IEEE Transactions on Ultrasonics, Ferroelectrics, and Frequency Control, Vol. 72, No. 6, pp. 806-816, 2025.
2024
J. Xia, Z. Wang, R. Becker, F. Li, S. Yang, J. Rufo, S.P. Zhang, C. Chen, Y. Gu, R.
Zhong, P. Lee, D. Wong, L.P. Lee, and T.J. Huang, “Super-resolution virus isolation
by Bessel beam excitation separation technology: BEST”, ACS nano, Vol. 18, No. 33, pp. 22596-22607, 2024.
M. Wu, Z. Ma, X. Xu, B. Lu, Y. Gu, J. Yoon, J. Xia, Z. Ma, N. Upreti, I.J. Anwar,
S.J. Knechtle, E. Chambers, J. Kwun, L.P. Lee, T.J. Huang, “Acoustofluidic-based therapeutic
apheresis system”, Nature Communications, Vol. 15, No. 1, pp. 6854, 2024.
Z. Ma, J. Xia, N. Upreti, E. David, J. Rufo, Y. Gu, K. Yang, S. Yang, X. Xu, J. Kwun,
E. Chambers, T.J. Huang, “An acoustofluidic device for the automated separation of
platelet-reduced plasma from whole blood”, Microsystems & Nanoengineering, Vol. 10, No. 1, pp. 83, 2024.
T. Naquin, A. Canning, Y. Gu, J. Chen, C. Naquin, J. Xia, B. Lu, S. Yang, A. Koroza,
K. Lin, H. Wang, W. Jeck, L.P. Lee, T.J. Huang, “Acoustic separation and concentration
of exosomes for nucleotide detection: ASCENDx”, Science Advances, Vol. 10, No. 10, eadm8597, 2024.
J. Rufo, P. Zhang, Z. Wang, Y. Gu, K. Yang, C. Chen, R. Zhong, K. Jin, J. Wu, Y. Ouyang,
Y. Sadovsky, L.P. Lee, T.J. Huang, “High-yield and rapid isolation of extracellular
vesicles by flocculation via orbital acoustic trapping: FLOAT”, Microsystems & Nanoengineering, Vol. 10, No. 1, pp. 1, 2024.
2023
Y. Gu*, V. Kumar, E.G.S.K. Dayavansha, S. Schoen, E. Feleppa, R. Tadross, M.H. Wang,
M.J. Washburn, K. Thomenius, A.E. Samir, “Acoustic diffraction-resistant adaptive
profile technology (ADAPT) for elasticity imaging”, Science Advances, Vol. 9, No. 44, eadi6129, 2023. (*Corresponding Author, highlighted by 4 News Media)
A. Ozturk, V. Kumar, T. Pierce, Q. Li, M. Baikpour, I. Rosado-Mendez, M. Wang, P.
Guo, S. Schoen, Y. Gu, E.G.S.K. Dayavansha, J. Grajo, A. Samir, “The Future is Beyond
Bright: The Evolving Role of Quantitative Ultrasound for Fatty Liver Disease”, Vol.
309, No. 2, e223146, Radiology, 2023.
S. Schoen, V. Kumar, Y. Gu, E.G.S.K. Dayavansha, R. Tadross, M. Washburn, K. Thomenius,
A. Samir, “Efficient Aberration Correction via Optimal Bulk Speed of Sound Compensation”,
arXiv preprint arXiv:2303.02018, 2023.
2022
J. Zhang, C. Chen, R. Becker, J. Rufo, S. Yang, J. Mai, P. Zhang, Y. Gu, Z. Wang,
Z. Ma, J. Xia, N. Hao, Z. Tian, D. T. W. Wong, Y. Sadovsky, L. P. Lee, T. J. Huang,
“A solution to the biophysical fractionation of extracellular vesicles: Acoustic Nanoscale
Separation via Wave-pillar Excitation Resonance (ANSWER)”, Science Advances, Vol. 8, No. 47, eade0640, 2022.
Z. Wang, J. Rich, N. Hao, Y. Gu, C. Chen, S. Yang, P. Zhang, T. J. Huang, “Acoustofluidics
for simultaneous nanoparticle-based drug loading and exosome encapsulation”, Microsystems & Nanoengineering, Vol. 8, No. 1, pp. 1-11, 2022.
2021
P. Zhang, J. Rufo, C. Chen, J. Xia, Z. Tian, L. Zhang, N. Hao, Z. Zhong, Y. Gu, K.
Chakrabarty, and T. J. Huang, “Acoustoelectronic nanotweezers enable dynamic and large-scale
control of nanomaterials”, Nature Communications, Vol. 12, No. 1, pp. 1-10, 2021. (highlighted by 13 News Media)
C. Chen, Y. Gu, J. Philippe, P. Zhang, H. Bachman, J. Zhang, J. Mai, J. Rufo, J. Rawls,
E. Davis, N. Katsanis, and T. J. Huang, “Acoustofluidic rotational tweezing enables
high-speed contactless morphological phenotyping of zebrafish larvae”, Nature Communications, Vol. 12, pp. 1-13, 2021.
H. Zhu, P. Zhang, Z. Zhong, J. Xia, J. Rich, J. Mai, X. Su, Z. Tian, H. Bachman, J.
Rufo, Y. Gu, P. Kang, K. Chakrabarty, T. P. Witelski, and T. J. Huang, “Acoustohydrodynamic
tweezers via spatial arrangement of streaming vortices”, Science Advances, Vol. 7, No. 2, eabc7885, 2021. (highlighted by Nature)
Y. Gu, C. Chen, Z. Mao, H. Bachman, R. Becker, J. Rufo, Z. Wang, P. Zhang, J. Mai,
S. Yang, J. Zhang, S. Zhao, Y. Ouyang, D. T. W. Wong, Y. Sadovsky, and T. J. Huang,
“Acoustofluidic centrifuge for nanoparticle enrichment and separation”, Science Advances, Vol. 7, No. 1, eabc0467, 2021. (highlighted by 16 News Media)
2020
Z. Tian, Z. Wang, P. Zhang, T. D. Naquin, J. Mai, Y. Wu, S. Yang, Y. Gu, H. Bachman,
Y. Liang, Z. Yu, and T. J. Huang, “Generating multifunctional acoustic tweezers in
petri dishes for contactless, precise manipulation of bioparticles”, Science Advances,
Vol. 6, No. 37, eabb0494, 2020.
P. Zhang, C. Chen, X. Su, J. Mai, Y. Gu, Z. Tian, H. Zhu, Z. Zhong, H. Fu, S. Yang,
K. Chakrabarty, and T. J. Huang, “Acoustic streaming vortices enable contactless,
digital control of droplets”, Science Advances, Vol 6, No. 24, eaba0606, 2020. (highlighted as News Report by 7 News Media)
Y. Gu, C. Chen, J. Rufo, C. Shen, Z. Wang, P. H. Huang, H. Fu, P. Zhang, S. A. Cummer,
Z. Tian, and T. J. Huang, “Acoustofluidic holography for micro- to nano- scale particle
manipulation”, ACS Nano, Vol. 14, pp. 14635-14645, 2020.
S. Zhao, M. Wu, S. Yang, Y. Wu, Y. Gu, C. Chen, J. Ye, Z. Xie, Z. Tian, H. Bachman,
P. H. Huang, J. Xia, S. P. Zhang, H. Zhang, and T. J. Huang, A disposable acoustofluidic
chip for nano/micro particle separation using unidirectional acoustic transducers,
Lab on a Chip, Vol 20, pp. 1298-1308, 2020.
H. Bachman, Y. Gu, J. Rufo, S. Yang, Z. Tian, P. H. Huang, L. Yu, and T. J. Huang,
“Low-frequency flexural wave based microparticle manipulation”, Lab on a Chip, Vol. 20, pp. 1281-1289, 2020.
2019
Z. Tian, S. Yang, P. H. Huang, Z. Wang, P. Zhang, Y. Gu, H. Bachman, C. Chen, M. Wu,
Y. Xie and T. J. Huang, “Wavenumber-spiral acoustic tweezers for dynamic and reconfigurable
manipulation of particles and cells”, Science Advances, Vol. 5, No. 5, eaau6062, 2019.
Z. Tian, C. Shen, J. Li, E. Reit, Y. Gu, H. Fu, S. A. Cummer, T. J. Huang, “Programmable
Acoustic Metasurfaces”, Advanced Functional Materials, Vol. 29, pp. 1808489, 2019.
P. Zhang, C. Chen, F. Guo, J. Philippec, Y. Gu, Z. Tian, H. Bachman, L. Ren, S. Yang,
Z. Zhong, P. H. Huang, N. Katsanis, K. Chakrabarty, and T. J. Huang, “Contactless,
programmable acoustofluidic manipulation of objects on water”, Lab on a Chip, Vol. 19, pp. 3397-3404, 2019.
S. Zhao, W. He, Z. Ma, P. Liu, P. H. Huang, H. Bachman, L. Wang, S. Yang, Z. Tian,
Z. Wang, Y. Gu, Z. Xie, and T. J. Huang, On-Chip stool liquefaction via acoustofluidics,
Lab on a Chip, Vol. 19, pp. 941-947, 2019. (featured as front cover image)
Y. Gu, C. Chen, Z. Wang, P. H. Huang, H. Fu, L. Wang, M. Wu, Y. Chen, T. Gao, J. Gong,
J. Kwun, G. M. Arepally, and T. J. Huang, “Plastic-based acoustofluidic devices for
high-throughput, biocompatible platelet separation”, Lab on a Chip, Vol. 19, pp. 394-402, 2019. (featured as front cover image)
2018
A. Ozcelik, J. Rufo, F. Guo, Y. Gu, P. Li, J. Lata, and T. J. Huang, “Acoustic tweezers
for the life sciences”, Nature Methods, Vol. 15, pp. 1021-1028, 2018.
C. Chen, S. P. Zhang, Z. Mao, N. Nama, Y. Gu, P. H. Huang, Y. Jing, X. Guo, F. Costanzo
and T. J. Huang, “Three-dimensional numerical simulation and experimental investigation
of boundary-driven streaming in surface acoustic wave microfluidics”, Lab on a Chip, Vol. 18, pp. 3645-3654, 2018.
2017
S. Liu, J. Wu, Y. Gu, X. Guo, J. Tu, D. Xu, and D. Zhang, “Ambient pressure evaluation
through sub-harmonic response of chirp-sonicated microbubbles”, Ultrasound in medicine
& biology, Vol. 43, pp. 332-340, 2017.
2016
C. Chen, Y. Gu, J. Tu, X. Guo, D. Zhang, “Microbubble oscillating in a microvessel
filled with viscous fluid: A finite element modeling study”, Ultrasonics, Vol. 66, pp. 54-64, 2016.
Y. Gu, C. Chen, J. Tu, X. Guo, H. Wu, and D. Zhang, “Harmonic responses and cavitation
activity of encapsulated microbubbles coupled with magnetic nanoparticles”, Ultrasonics Sonochemistry, Vol. 29, pp. 309-316, 2016.